| Term | Definition |
|
infection |
number one cause of death worldwide |
|
mechanism of action |
direct damage of cells; cell dysfunctional because of the accumulation of pathogenic substances and toxin production |
|
infectivity |
ability of the pathogen to invade and multiply in the individual |
|
pathogenicity |
ability of an agent to produce disease-success depends on its speed of reproduction, extent of tissue damage, and production of toxins |
|
toxigenicity |
factor important in determining a pathogen's virulence, such as production of soluble toxins or endotoxin |
|
immunogeniciy |
ability of pathogens to induce immune response |
|
virulence |
protency of a pathogen measured in terms of number of microorganisms or micrograms of toxin required to kill a host |
|
spread of infection |
site of entry, route of entry, mechanism of infection |
|
site of entry |
skin and mucous membrane; alimentary,genitourinary and respiratory tracts; eyes and ears |
|
route of entry |
direct contact, inhalation, ingestion, vector bite |
|
mechanism of infection |
adhesins, enzyme release, phagocytic escap, acid resistance |
|
bacteria |
can be aerobic or anaerobic and motile or immotile |
|
cocci |
spherical shaped |
|
bacilli |
rod like forms |
|
spirochetes |
spiral forms |
|
septicemia |
the presence of bacteria in the blood and is caused by a failure of the body's defences, can travel through body and cause shock |
|
virus |
microorganism consisting of a nucleic acid protected from the environment by layers of proteins, cannot survive long outside of a cell and have no metabolism |
|
virus disease |
most common affliction of humans, transfer from organism to organism, trasmit through droplets, direct contact, blood, airborn, sexual-body fluid |
|
fungal disease |
large microorganism with thick walls, grow as single-celled yeasts (spheres) or multi-celled molds (filaments of hyphae), present on skin |
|
labratory signs |
CBC (L shift), elevated WBC, neutrophils |
|
culture |
tells you the organism |
|
sensitivity |
tells which antibiotics it is resistant to and those it is sensitive to |
|
post op fever |
wind, water, wound, walking, wonder drugs |
|
symptoms of infection |
fatigue, malaise, loss of concentration, weakness; loss of appetite; area specific; pain |
|
immune deficiencies |
diabetes, stress, infancy, aging, malnutrition |